The Endocannabinoid System Explained: Omega-3/6 Balance, Natural Health, and God’s Design

Hello everybody, and welcome to another version of Chip Talks Health. Today we’re diving into one of the most important things you can learn about your body — the endocannabinoid system (ECS).

If you’ve heard of cannabis, you’ve probably heard people mention the ECS in passing. But I want you to put cannabis aside for a minute. The endocannabinoid system is not about marijuana — it’s about you. It’s about how your body was designed to regulate, repair, and heal itself.

Here’s the problem: most doctors, PhDs, and dietitians have never been taught this system. It’s not in medical school curriculum. And that’s insane, because the ECS is your master regulatory system. It controls your nervous system, your immune system, your digestion, even the energy status of your cells.

So let’s talk about how the ECS works, why Omega-3 and Omega-6 fats are critical, and how we can reclaim our health by remembering we were designed perfectly — not broken.

Think of the ECS as the body’s communication and balancing network. It’s made up of endocannabinoids (molecules your body makes), receptors (like CB1 and CB2), and enzymes that build or break those molecules down.

• ECS helps regulate pain, inflammation, sleep, mood, memory, appetite, and immune response.

• It connects with every organ and every cell in your body.

• Scientists have found ECS receptors not just on nerve cells, but on mitochondria (your cell’s power plants) and even organelles inside cells.

That means the ECS isn’t just “part” of how you work — it’s central to everything.

You’d think if science discovered a master system that controls your nervous system, every medical school would be rushing to teach it, right? Nope.

Here’s the truth: pharma doesn’t want it taught. There’s no drug model for giving people the knowledge that their body already knows how to heal. So the Endocannabinoid System gets a few hours of lecture time in pharmacology, and that’s it.

That’s why I teach this — because you deserve to know how your body works.

When your Omega balance is off, your ECS makes the wrong signals. Here’s how that looks:

• Too much Omega-6 → more PGE2 prostaglandins (these cause inflammation and pain).

• Balanced Omega-3 → more PGE3 prostaglandins (these promote healing).

That’s why people who eat high Omega-6 diets are more prone to pain, autoimmunity, and chronic disease.

It’s also why cannabis constituents like CBDA can safely block pain pathways (the COX enzymes), without the damage of ibuprofen or Tylenol. Cannabis is like a screwdriver that can adjust the ECS — but diet is the foundation.

Here’s the amazing part: your ECS regulates not just cells, but organs and rhythms.

• Around 10am and 3pm, CB1 receptors increase in the gut → you feel hungry.

• Around 11am–1pm, your body is set to repair your heart. Eat lunch then, and you shift energy away from repair.

• Around 7pm, the ECS cues liver repair.

Even your circadian rhythm — syncing with the sun — is mediated by ECS signals.

That’s how deep this runs.

We’re in a health crisis because we’ve ignored the very system designed to protect us.

Here’s why you should care:

• The ECS is your master regulator.

• The Omega-3/6 balance you eat every single day determines whether you inflame or heal.

• Cannabis is one tool — but it’s not the whole system.

• Pharma and FDA won’t teach you this — but you can learn it.

And this isn’t just theory. Cindy and I hold U.S. Patent 10,646,535 for modulating the endocannabinoid system to achieve desired health and wellness effects. We’ve built TrueMedX products and Neighborly Wellness services around this knowledge.