Unlocking the Secrets to Weight Loss - Chip Talks Health S5E8

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Hello everyone, and welcome to another exciting version of the Chip Talks podcast.

You probably know someone who might need to lose some weight — or maybe that person is you. Today, we’re going to talk about obesity: why it happens, what’s really going on inside the body, and how you can begin changing that situation yourself — without drugs like Ozempic or Mounjaro.

We’ll dig deep into what obesity is, what happens to people who struggle with it, and how we can start restoring balance naturally.

A Personal Connection

When I was young, between the ages of 10 and 14, I was overweight — not morbidly, but enough that I would have been classified as obese.

Like many kids, I got made fun of, called names, and constantly compared myself to others. I wanted to be thinner, to look like everyone else.

But no matter what I did, I couldn’t lose the weight.

Then in my teens, I started using marijuana — not something I recommend — and the weight dropped off quickly. I also started smoking cigarettes (again, not a great idea).

Looking back now, I understand why that happened. At the time, I didn’t realize how much my body’s chemistry — specifically the endocannabinoid system — was involved.

I know the frustration of trying everything and still not seeing results. So I have real empathy for anyone going through that battle.

The Bigger Picture: Metabolic Syndrome

Today, over 50% of U.S. adults are overweight or obese.

The medical world uses the term “metabolic syndrome” to describe a cluster of issues that include obesity, diabetes, and heart disease.

We’ll break those down individually over time, but right now we’re focusing on weight loss — and it all starts with understanding how your body knows when you’re full or hungry.

Your Body’s Master Regulator: The Endocannabinoid System

That hunger–fullness control happens through something called the endocannabinoid system (ECS) — your master regulatory system.

Now, this has nothing to do with marijuana. Don’t get hung up on the name.

The ECS exists inside you, your dog, your cat, even your fish. It’s what helps the body maintain balance.

And it’s fueled not by cannabis, but by dietary fats — omega-3 and omega-6 fatty acids you get from olive oil, avocados, nuts, and seeds.

When the ECS is working right, it tells your brain:

“I’m hungry.”
“I’m full.”
“I have enough nutrients.”

But when it’s out of tune, those signals go haywire — and that’s when overeating and cravings start.

What Ozempic Really Does

We’ve all heard of Ozempic, Wegovy, or Mounjaro — drugs that claim to help with weight loss.

Here’s what they actually do: they artificially stimulate your satiety molecules — hormones like GLP-1, GIP, and Peptide YY.

Basically, they trick your brain into thinking you’re full.

And yes, that can lead to weight loss… but it also overrides your natural regulatory system and creates new problems downstream.

Instead of flipping half a dozen switches in every cell with a drug, the ECS flips one master switch that balances them all — naturally.

Nature’s Version of Ozempic: Olive Oil

Inside your body, oleic acid (found in olive oil and avocados) can convert into oleoylethanolamide (OEA) — a natural endocannabinoid-like molecule.

OEA binds to the GPR120 receptor and helps you feel full — releasing those same hormones (GLP-1, GIP, and PYY) without injections.

So theoretically, if you’re feeling ravenous at the wrong time of day, a tablespoon of olive oil should help satisfy that signal.

Are You Really Hungry — or Just Out of Rhythm?

You can go 40 days without eating. Most of us have enough stored nutrients.

So why do we feel “hungry” around 10 a.m. and 3 p.m.?

Because your body runs on an internal clock — sometimes called the Chinese body clock.

At certain hours, your body shifts energy focus to different organs. Around mid-morning and mid-afternoon, your gut expresses CB1 receptors, signaling that “now would be a good time to eat” — not that you must eat.

That’s why intermittent fasting works so well — it syncs your eating with your body’s rhythm.

When the Gut Biome Hijacks Hunger

Here’s where things get interesting — sometimes the hunger isn’t you at all.

Certain gut bacteria, especially Firmicutes, can overgrow and start demanding food for themselves. They can even hijack your dopamine and serotonin pathways to reward you for eating sugar and junk food.

This is why you might find yourself in the cookie aisle wondering, “What am I doing here?”

It’s not a lack of willpower — it’s biology.

How to Break the Loop

At TrueMedX, we developed a product called FAST (now part of the Metabolic Balance system).

It’s designed to naturally increase your OEA levels, quiet gut “noise,” and help restore that fullness feedback loop — safely and effectively using food-based ingredients.

It works because we target the root cause: communication between the ECS, the gut biome, and your metabolic pathways.

If You Want to Do It Yourself

You can also start balancing things naturally:

Eat more fermented foods — sauerkraut, kimchi, apple cider vinegar, or naturally pickled onions. These support Bacteroidetes, the beneficial bacteria that reduce cravings.
Balance your fats — we eat too many omega-6 oils (corn, soy, canola) and not enough omega-3s. Try adding flax, chia, camelina, or fish oil.
Support fasting windows — allow your body time to reset and rebalance the ECS.

The Omega Connection

Omega-3 and Omega-6 fats are the building blocks of your ECS.

When your diet is heavy in omega-6 (typical in Western diets), your ECS becomes inflamed and less responsive.

People who are obese often have higher circulating endocannabinoids — yet less control. It’s like your body is trying to regulate itself but can’t get through the noise.

Restoring omega balance helps quiet that noise and restore ECS tone.